Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGAV | P06756 | 3/20 | 0.45 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251811 | 0.84 | ITGB3 (0.45) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL15271011 | 0.82 | HTR2C (0.58) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL2435013 | 0.81 | HTR2C (0.59) | HTR2CFFAR1ITGB3ITGAVITGB6 | |
| SCHEMBL22169320 | 0.80 | ITGB3 (0.45) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL21847837 | 0.80 | ITGB3 (0.45) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL27404054 | 0.78 | ITGB3 (0.42) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL27404045 | 0.78 | HTR2C (0.59) | HTR2CHTR2AHTR2BITGB3ITGAV | |
| SCHEMBL11965119 | 0.77 | HTR2C (0.63) | HTR2CHTR2AHTR2BFFAR1ALDH1A1 | |
| SCHEMBL11902887 | 0.77 | HTR2C (0.63) | HTR2CHTR2AHTR2BFFAR1ALDH1A1 | |
| SCHEMBL27404050 | 0.77 | ITGB3 (0.47) | HTR2CITGB3ITGAVITGB6ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138104-A1 | Peptides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138104-A1 | Peptides | PTMS, VIP, CPB1 | HTR2C 2164/4885HTR2A 1473/4885HTR2B 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.