Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786139 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL19155762 | 0.81 | MAPT (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL34473958 | 0.79 | HTR2A (0.34) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL12300309 | 0.78 | L3MBTL1 (0.42) | MAPTALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL18052935 | 0.77 | MAPT (0.41) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL11709637 | 0.76 | IDO1 (0.41) | ALDH1A1TDP1PDE4DTSHRTP53 | |
| SCHEMBL27999879 | 0.76 | MAPT (0.46) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL9672377 | 0.76 | IDO1 (0.48) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL11153759 | 0.75 | TSHR (0.39) | MAPTALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL22787328 | 0.75 | MAPT (0.44) | MAPTALDH1A1HSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524600-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS | SANOFI SA (FR) | 2021-11-17 | — | — | EP | disclosed |