Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719155 | 0.79 | HPGD (0.40) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL12300309 | 0.78 | L3MBTL1 (0.42) | TSHRALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL19155762 | 0.77 | MAPT (0.41) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10726742 | 0.76 | KDM4E (0.40) | ALDH1A1HPGDKDM4EMAPK1L3MBTL1 | |
| SCHEMBL24022121 | 0.75 | MAPT (0.52) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL22787328 | 0.75 | MAPT (0.44) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3785688 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1MAPTRAB9A | |
| SCHEMBL7735282 | 0.72 | L3MBTL1 (0.44) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL18052935 | 0.72 | MAPT (0.41) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL19154831 | 0.72 | TSHR (0.37) | TSHRALDH1A1HPGDKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389416-A | DIURETICS | ABBOTT LABORATORIES (US) | 1983-06-21 | — | — | US | disclosed |