Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.56 |
| ▸ | CCR8 | P51685 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | BRS3 | P32247 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631394 | 0.88 | RAB9A (0.52) | RAB9ASMN1; SMN2METAP2MAPTNPC1 | |
| SCHEMBL3422361 | 0.85 | CCR1 (0.75) | CCR1CCR8RAB9ACYP2A6METAP2 | |
| SCHEMBL12970400 | 0.83 | CCR1 (0.54) | CCR1CCR8RAB9ACYP2A6BRS3 | |
| SCHEMBL171757 | 0.80 | CCR1 (0.50) | CCR1CCR8RAB9ACYP2A6BRS3 | |
| SCHEMBL2614970 | 0.79 | CCR1 (0.65) | CCR1CCR8RAB9ASMN1; SMN2CYP2A6 | |
| SCHEMBL12170347 | 0.79 | ASIC3 (0.60) | RAB9ASMN1; SMN2BRS3METAP2MAPT | |
| SCHEMBL19407092 | 0.79 | RAB9A (0.44) | RAB9ASMN1; SMN2METAP2MAPTNPC1 | |
| SCHEMBL12270035 | 0.79 | CCR1 (0.48) | CCR1CCR8RAB9ACYP2A6BRS3 | |
| SCHEMBL12318156 | 0.79 | CCR1 (0.48) | CCR1CCR8CYP2A6BRS3METAP2 | |
| SCHEMBL2189142 | 0.78 | KMT2A (0.62) | CCR1CCR8RAB9ACYP2A6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3509589-B1 | NOVEL USES | INTRA CELLULAR THERAPIES INC (US) | 2021-11-17 | — | — | EP | disclosed |