Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044394 | 0.84 | RECQL (0.45) | RAB9ALMNARECQLPDE4DPDE4A | |
| SCHEMBL24022848 | 0.80 | HDAC1 (0.50) | RAB9ALMNAHTTKCNQ3KCNQ2 | |
| SCHEMBL2326648 | 0.80 | RECQL (0.68) | RAB9ALMNAHTTMAPK1RECQL | |
| SCHEMBL2326651 | 0.80 | RECQL (0.68) | RAB9ALMNAHTTMAPK1RECQL | |
| SCHEMBL22043785 | 0.78 | KDM4E (0.42) | CYP1A2CYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL22044250 | 0.77 | SMN1; SMN2 (0.44) | RAB9ALMNAHTTMAOBAR | |
| SCHEMBL22043759 | 0.75 | DGAT1 (0.46) | KDM1AMEN1KMT2A | |
| SCHEMBL22043753 | 0.73 | EPHX2 (0.39) | RAB9ALMNAHTTMAPK1ALDH1A1 | |
| SCHEMBL24022755 | 0.73 | NEU3 (0.46) | HTTMAPK1 | |
| SCHEMBL22044268 | 0.73 | ACHE (0.47) | RAB9ALMNAHTTMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |