Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022845 | 0.84 | RAB9A (0.50) | RECQLPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24022749 | 0.82 | PRSS1 (0.48) | MAPTRAB9ANPC1POLBLMNA | |
| SCHEMBL6608276 | 0.79 | RECQL (0.70) | RECQLALOX15PDE4APDE4BPDE4C | |
| SCHEMBL24022830 | 0.77 | MKNK1 (0.38) | PDE4DMAPTRAB9ANPC1LMNA | |
| SCHEMBL22044268 | 0.77 | ACHE (0.47) | RECQLMAPTRAB9ANPC1POLB | |
| SCHEMBL24022848 | 0.75 | HDAC1 (0.50) | MAPTRAB9ANPC1LMNATSHR | |
| SCHEMBL24039027 | 0.74 | NEU3 (0.48) | MAPTRAB9ANPC1TSHR | |
| SCHEMBL22043779 | 0.73 | CYP2D6 (0.47) | MAPTRAB9ANPC1POLBLMNA | |
| SCHEMBL15947332 | 0.72 | ALOX15 (0.60) | RECQLALOX15PDE4APDE4BPDE4C | |
| SCHEMBL17833298 | 0.72 | ALOX15 (0.51) | RECQLALOX15PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| WO-2020108720-A1 | NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING | Københavns Universitet (DK) | 2020-06-04 | — | — | WO | disclosed |