Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 3/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.38 |
| ▸ | CYP2A7 | P20853 | 3/20 | 0.38 |
| ▸ | CYP3A7 | P24462 | 3/20 | 0.38 |
| ▸ | CYP2F1 | P24903 | 3/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066918 | 1.00 | MAPT (0.55) | MAPTKDM4ETP53CYP1B1CYP1A1 | |
| SCHEMBL24022855 | 0.80 | TP53 (0.56) | MAPTKDM4ETP53CYP1B1CYP1A1 | |
| SCHEMBL22044476 | 0.79 | KDM4E (0.55) | MAPTKDM4ETP53CYP1B1CYP1A1 | |
| SCHEMBL22044461 | 0.76 | KDM4E (0.37) | MAPTKDM4ETP53 | |
| SCHEMBL22044269 | 0.72 | KDM4E (0.33) | MAPTKDM4ETP53 | |
| SCHEMBL607853 | 0.71 | MAPT (1.00) | MAPTKDM4ETP53ALDH1A1KMT2A | |
| SCHEMBL388181 | 0.71 | ALDH1A1 (0.69) | CYP1B1CYP1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL811852 | 0.71 | ALDH1A1 (0.59) | CYP1B1CYP1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24022748 | 0.67 | THRB (0.34) | MAPTKDM4ETP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL24022824 | 0.67 | DHODH (0.34) | MAPTKDM4ETP53CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |