SCHEMBL388181

SCHEMBL388181

COc1cc(I)cc(OC)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.69
CYP1A1 P04798 7/20 0.50
CYP1B1 Q16678 7/20 0.50
CYP1A2 P05177 4/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2E1 P05181 2/20 0.44
CYP2C8 P10632 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2A6 P11509 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP4B1 P13584 2/20 0.44
CYP2B6 P20813 2/20 0.44
CYP3A5 P20815 2/20 0.44
CYP2A7 P20853 2/20 0.44
CYP3A7 P24462 2/20 0.44
CYP2F1 P24903 2/20 0.44
CYP2C18 P33260 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2J2 P51589 2/20 0.44
CYP4F2 P78329 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811852 0.94 ALDH1A1 (0.59) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL388119 0.84 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
1,3,5-Trimethoxybenzene SCHEMBL28493 0.83 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL600497 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP3A4CYP19A1
SCHEMBL13786716 0.82 CYP3A4 (0.50) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL1710751 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL16955152 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL15936181 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP3A4CA12
SCHEMBL17204349 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL30074410 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP3A4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813454-B Synthetic method of pterostilbene 珠海市柏瑞医药科技有限公司 2024-03-22 CN claimed
CN-116813454-A Synthetic method of pterostilbene 珠海市柏瑞医药科技有限公司 2023-09-29 CN claimed
CN-113201119-A Red light polymer based on carbazole phenanthroimidazole and preparation method thereof 广州万物物联科技有限公司 2021-08-03 CN claimed
WO-2021096496-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2021-05-20 WO claimed
EP-3790862-A2 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS Colorado State University Research Foundation (US) 2021-03-17 EP claimed
CN-112262128-A Method for forming aryl carbon-nitrogen bond by illumination and photoreactor for carrying out the reaction 科罗拉多州立大学研究基金会 2021-01-22 CN claimed
US-20200147581-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2020-05-14 US claimed
WO-2020036661-A2 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2020-02-20 WO claimed
US-20190345122-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2019-11-14 US claimed
CN-119320374-B Method for synthesizing 3-sulfonyl substituted chromone derivative by photocatalysis JIANG University OF TECHNOLOGY (CN) 2026-05-26 CN disclosed
CN-122059997-A Palladium complex modified by norbornane skeleton monophosphine ligand, and preparation method and application thereof 滨州魏桥国科高等技术研究院 2026-05-19 CN disclosed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
EP-4688796-A1 ARYL-HETEROCYCLE-PYRROLE CATALYSTS FOR OLEFIN POLYMERIZATION Dow Global Technologies LLC (US) 2026-02-11 EP disclosed
US-20250276966-A1 Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives PFIZER (US) 2025-09-04 US disclosed
EP-0850948-B1 Propiophenone derivatives and process for preparing the same TANABE SEIYAKU CO (JP) 2002-04-24 EP disclosed
WO-2002013764-A2 METHODS FOR TREATING SUBJECTS INFECTED WITH A HERPES VIRUS OR NEISSERIA GONORRHEAE NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE (US) 2002-02-21 WO disclosed
WO-2001019825-A1 PTERIDINONES AS KINASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-03-22 WO disclosed
US-6048842-A ANTIDIABETIC AGENT TANABE SEIYAKU CO., LTD. (JP) 2000-04-11 US disclosed
CN-1190097-A Propiophenone derivatives and process for preparing the same TANABE SEIYAKU CO (JP) 1998-08-12 CN disclosed
EP-0850948-A1 Propiophenone derivatives and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1998-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276966-A1 Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives CCNI, MKI67, CCNA1 ALDH1A1 792/4885CYP1A1 905/4885CYP1B1 560/4885
US-20190345122-A1 METHODS FOR FORMING ARYL CARBON-NITROGEN BONDS USING LIGHT AND PHOTOREACTORS USEFUL FOR CONDUCTING SUCH REACTIONS TYR, CRY2, CRY1 ALDH1A1 1574/4885CYP1A1 554/4885CYP1B1 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.