Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852389 | 0.83 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL15467260 | 0.78 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL12562965 | 0.72 | CHRNB2 (0.40) | MAPK1 | |
| SCHEMBL12093049 | 0.72 | — | — | |
| SCHEMBL2611974 | 0.72 | — | — | |
| SCHEMBL12687558 | 0.72 | — | — | |
| SCHEMBL623971 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL744751 | 0.69 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL1461345 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL28452 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550258-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbvie Inc. (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119345-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-09-29 | — | — | WO | disclosed |