Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17246426 | 0.88 | KMT2A (0.36) | KMT2AMAT2AMAPTGAALIMK1 | |
| SCHEMBL24026135 | 0.85 | ESR2 (0.36) | ESR2KMT2AALOX5ESR1MAT2A | |
| SCHEMBL21328047 | 0.85 | MAT2A (0.35) | ESR2KMT2AESR1MAT2AMAPT | |
| SCHEMBL24026096 | 0.83 | DYRK1A (0.40) | KMT2AMAPTKDM4EMEN1RAB9A | |
| SCHEMBL24026175 | 0.82 | KMT2A (0.37) | ESR2KMT2AMAT2AMAPTGAA | |
| SCHEMBL24026092 | 0.82 | MAT2A (0.36) | ESR2KMT2AMAT2AMAPTGAA | |
| SCHEMBL17705507 | 0.79 | KMT2A (0.38) | KMT2AMAPTGAALIMK1POLB | |
| SCHEMBL29992464 | 0.78 | MAT2A (0.40) | KMT2AMAT2AMAPTGAAPOLB | |
| SCHEMBL15063380 | 0.78 | MAT2A (0.40) | KMT2AMAT2AMAPTGAAPOLB | |
| SCHEMBL15126988 | 0.78 | KMT2A (0.34) | KMT2AMAPTGAALIMK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | UNIV ARIZONA STATE (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | PDCD2L, PDCD1, PDCD4 | ESR2 3778/4885KMT2A 2798/4885ALOX5 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.