Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24026092 | 0.95 | MAT2A (0.36) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL17228887 | 0.89 | KMT2A (0.38) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL17071012 | 0.85 | KMT2A (0.36) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL17246581 | 0.84 | KMT2A (0.37) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL17246476 | 0.84 | GPR3 (0.38) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL24026098 | 0.82 | ESR2 (0.39) | KMT2AMAPTALDH1A1RAB9AHSD17B10 | |
| SCHEMBL15063380 | 0.82 | MAT2A (0.40) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL29992464 | 0.82 | MAT2A (0.40) | KMT2AMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL24026135 | 0.81 | ESR2 (0.36) | KMT2AMAPTALDH1A1RAB9AHSD17B10 | |
| SCHEMBL21328047 | 0.81 | MAT2A (0.35) | KMT2AMAPTALDH1A1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | UNIV ARIZONA STATE (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | PDCD2L, PDCD1, PDCD4 | KMT2A 2798/4885MAPT 425/4885ALDH1A1 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.