SCHEMBL21328047

SCHEMBL21328047

Oc1ccc2c3ccc4sc5ccccc5c4c3n(-c3ccccn3)c2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 2/20 0.35
▸ MAOA P21397 1/20 0.34
▸ MAOB P27338 1/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ ESR2 Q92731 2/20 0.33
▸ BCHE P06276 2/20 0.32
▸ ACHE P22303 2/20 0.32
▸ BACE1 P56817 2/20 0.32
▸ MAPT P10636 3/20 0.32
▸ GAA P10253 2/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ POLB P06746 2/20 0.32
▸ MCL1 Q07820 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ PKM P14618 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ NLRP3 Q96P20 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ DUSP3 P51452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246468 0.88 KMT2A (0.35) MAT2AKMT2AACHEMAPTGAA
SCHEMBL24026137 0.86 MAT2A (0.35) MAT2AMAOAMAOBKMT2AESR2
SCHEMBL29309682 0.86 MAT2A (0.35) MAT2AKMT2AMAPTMEN1POLB
SCHEMBL21339169 0.85 MAT2A (0.34) MAT2AKMT2AMAPTMEN1POLB
SCHEMBL24026098 0.85 ESR2 (0.39) MAT2AKMT2AESR2MAPTGAA
SCHEMBL24026101 0.84 MAOA (0.31) MAOAMAOB
SCHEMBL21328046 0.84 KDM4E (0.43) MAT2AMAOAKMT2AACHEMAPT
SCHEMBL24026092 0.81 MAT2A (0.36) MAT2AMAOAMAOBKMT2AESR2
SCHEMBL24026175 0.81 KMT2A (0.37) MAT2AKMT2AESR2BCHEACHE
SCHEMBL15126919 0.81 KMT2A (0.35) MAT2AKMT2AMAPTGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-10-31 — — US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 — — US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 — — US disclosed
US-12037348-B2 Blue and narrow band green and red emitting metal complexes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-16 — — US disclosed
US-20210359224-A1 TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES UNIV ARIZONA STATE (US) 2021-11-18 — — US disclosed
US-20190276485-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-09-12 — — US disclosed
US-20190276485-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037348-B2 Blue and narrow band green and red emitting metal complexes OCIAD2, OCIAD1, ORC3 MAT2A 4790/4885MAOA 3647/4885MAOB 1955/4885
US-20210359224-A1 TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES PDCD2L, PDCD1, PDCD4 MAT2A 4806/4885MAOA 2892/4885MAOB 1615/4885
US-20240360169-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES OCIAD2, OCIAD1, ORC3 MAT2A 4790/4885MAOA 3647/4885MAOB 1955/4885
US-20190276485-A1 BLUE AND NARROW BAND GREEN AND RED EMITTING METAL COMPLEXES OCIAD2, OCIAD1, ORC3 MAT2A 4790/4885MAOA 3647/4885MAOB 1955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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