Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24026164 | 0.91 | KDM4E (0.39) | KDM4EHTTMAPTALDH1A1HPGD | |
| SCHEMBL24026226 | 0.91 | KDM4E (0.44) | KDM4EHTTMAPTALDH1A1HPGD | |
| SCHEMBL24026208 | 0.90 | KDM4E (0.43) | KDM4EHTTMAPTALDH1A1HPGD | |
| SCHEMBL15063446 | 0.87 | KDM4E (0.48) | KDM4EHTTMAPTALDH1A1HPGD | |
| SCHEMBL10027615 | 0.85 | KDM4E (0.52) | KDM4EHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17989831 | 0.83 | KDM4E (0.41) | KDM4EHTTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17248316 | 0.83 | KDM4E (0.46) | KDM4EHTTALDH1A1L3MBTL1POLB | |
| SCHEMBL17989805 | 0.83 | KDM4E (0.49) | KDM4EHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24026132 | 0.82 | KDM4E (0.41) | KDM4EHTTMAPTALDH1A1HPGD | |
| SCHEMBL20363738 | 0.82 | MAT2A (0.49) | KDM4EL3MBTL1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | UNIV ARIZONA STATE (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210359224-A1 | TETRADENTATE PLATINUM AND PALLADIUM COMPLEXES BASED ON BISCARBAZOLE AND ANALOGUES | PDCD2L, PDCD1, PDCD4 | KDM4E 3798/4885HTT 1580/4885MAPT 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.