SCHEMBL15063446

SCHEMBL15063446

COc1ccc2c3ccccc3n(-c3ccccn3)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
HTT P42858 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 1/20 0.48
DYRK1A Q13627 4/20 0.44
MAOA P21397 1/20 0.44
PDE10A Q9Y233 1/20 0.43
MAT2A P31153 2/20 0.41
MAPK1 P28482 2/20 0.40
NCOA1 Q15788 2/20 0.40
NCOA3 Q9Y6Q9 2/20 0.40
LMNA P02545 1/20 0.40
PABPC1 P11940 1/20 0.40
CASP3 P42574 1/20 0.40
SENP6 Q9GZR1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24026226 0.91 KDM4E (0.44) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL24026208 0.90 KDM4E (0.43) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL15063339 0.88 REN (0.41) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL23526100 0.87 REN (0.41) KDM4EALDH1A1MAPTHTTMEN1
SCHEMBL4872843 0.87 KDM4E (0.51) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL24026271 0.87 KDM4E (0.42) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL24026164 0.85 KDM4E (0.39) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL15063582 0.85 DYRK1A (0.47) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL30697391 0.84 HTT (0.43) KDM4EL3MBTL1ALDH1A1MAPTHTT
SCHEMBL27024577 0.84 HTT (0.43) KDM4EL3MBTL1ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844266-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-12-12 US disclosed
US-20230189631-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189631-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-11678564-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11678564-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-20220112231-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-14 US disclosed
US-20200280003-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-09-03 US disclosed
US-20190157579-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-23 US disclosed
US-9461254-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-04 US disclosed
US-9461254-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-04 US disclosed
US-9461254-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-04 US disclosed
US-20130168656-A1 CYCLOMETALLATED TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2013-07-04 US disclosed
US-20130168656-A1 CYCLOMETALLATED TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2013-07-04 US disclosed
US-20130168656-A1 CYCLOMETALLATED TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200280003-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYBA, CYC1, CRY1 KDM4E 1829/4885L3MBTL1 346/4885ALDH1A1 1190/4885
US-20220112231-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, LEF1 KDM4E 1291/4885L3MBTL1 116/4885ALDH1A1 27/4885
US-11678564-B2 Organometallic compound and organic light-emitting device including the same TPO, TTI1, MRPL11 KDM4E 3671/4885L3MBTL1 127/4885ALDH1A1 101/4885
US-20230189631-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE GPX1, LAGE3, CRY1 KDM4E 1202/4885L3MBTL1 133/4885ALDH1A1 13/4885
US-20190157579-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TPO, TTI1, MRPL11 KDM4E 3671/4885L3MBTL1 127/4885ALDH1A1 101/4885
US-11844266-B2 Organometallic compound and organic light-emitting device including the same CYBA, CYC1, CRY1 KDM4E 1829/4885L3MBTL1 346/4885ALDH1A1 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.