Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891264 | 0.79 | MEN1 (0.74) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL7046333 | 0.78 | TNKS2 (0.57) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL13035686 | 0.74 | MEN1 (1.00) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL7674927 | 0.70 | TNKS2 (1.00) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL16108431 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28440983 | 0.69 | LTA4H (0.47) | KDM4EALDH1A1GAAMAPTMEN1 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.69 | CA1 (1.00) | KDM4EALDH1A1GAAMAPTMEN1 | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.69 | CA1 (1.00) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL23784304 | 0.69 | RAB9A (0.46) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL24017073 | 0.68 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229571-A1 | IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2021-11-18 | — | — | WO | disclosed |