Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249457 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL5847543 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL4169505 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL5109143 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL1598051 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL190145 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL18754782 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL20812666 | 0.85 | OPRD1 (0.49) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL18872558 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRD1FPR3FPR2KDM1A | |
| SCHEMBL3040560 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2OPRD1FPR3FPR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183188-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. | 2023-06-15 | — | — | US | disclosed |
| WO-2021231726-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183188-A1 | ENPP1 MODULATORS AND USES THEREOF | ENPP1, ENPP2, ENPP3 | SMN1; SMN2 2314/4885OPRD1 2751/4885FPR3 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.