⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724335 | 0.78 | PIK3CD (0.32) | — | |
| SCHEMBL200995 | 0.77 | — | — | |
| SCHEMBL19383830 | 0.76 | ADH1B (0.31) | — | |
| SCHEMBL12328301 | 0.76 | ADH1B (0.31) | — | |
| SCHEMBL24793744 | 0.74 | — | — | |
| SCHEMBL28685451 | 0.74 | — | — | |
| SCHEMBL24299787 | 0.72 | HTR1A (0.32) | — | |
| Hydrochloric Acid SCHEMBL27883284 | 0.72 | CTSK (0.30) | — | |
| SCHEMBL8950236 | 0.70 | — | — | |
| SCHEMBL18763016 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545072-B1 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20160009770-A1 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-9044514-B2 | Lipid-peptide-polymer conjugates and nanoparticles thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-06-02 | — | — | US | disclosed |
| US-20130121917-A1 | Lipid-Peptide-Polymer Conjugates and Nanoparticles Thereof | LAWRENCE BERKELEY NATIONAL LABORATORY (US) | 2013-05-16 | — | — | US | disclosed |
| EP-2545072-A2 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | The Regents of the University of California (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112999-A2 | LIPID-PEPTIDE-POLYMER CONJUGATES AND NANOPARTICLES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-15 | — | — | WO | disclosed |