SCHEMBL240296

SCHEMBL240296

Nc1ccnc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432892 1.00
SCHEMBL240826 0.75 TAAR1 (0.48)
SCHEMBL7088779 0.74 ADORA2B (0.49)
SCHEMBL24003989 0.72 MEN1 (0.56)
SCHEMBL43935 0.72
SCHEMBL314105 0.72 ASIC3 (0.67)
SCHEMBL29370280 0.72
SCHEMBL1697620 0.72
SCHEMBL22068158 0.72 IDO1 (0.55)
SCHEMBL29518274 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950459-B Hydrogenation catalyst carrier and preparation method thereof, hydrogenation catalyst and preparation method thereof 中国石油天然气股份有限公司 2024-11-26 CN claimed
CN-114950459-A Hydrogenation catalyst carrier and preparation method thereof, hydrogenation catalyst and preparation method thereof 中国石油天然气股份有限公司 2022-08-30 CN claimed
WO-2010100050-A1 PYRIDINE-2-YL-CARBOXYLIC ACID AMIDES F. HOFFMANN-LA ROCHE AG (CH) 2010-09-10 WO claimed
US-20100227887-A1 PYRIDINE-2-YL CARBOXYLIC ACID AMIDES F. HOFFMANN-LA ROCHE AG (CH) 2010-09-09 US claimed
EP-4737442-A1 DIAMINOVINYLIDENE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAID COMPOUND, AND METHODS FOR USING THESE ADEKA CORPORATION (JP) 2026-05-06 EP disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
US-12503467-B2 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors IDEAYA BIOSCIENCES, INC. (US) 2025-12-23 US disclosed
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INST NAT SANTE RECH MED (FR) 2025-12-18 US disclosed
CN-116472047-B Arylamine derivative, preparation method and medical application thereof 中国医药研究开发中心有限公司 2025-06-17 CN disclosed
WO-2025096608-A1 EGFR COVALENT INHIBITION WITH MACROCYCLES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-05-08 WO disclosed
US-20250136558-A1 PYRAZINE COMPOUNDS AS IRREVERSIBLE INHIBITORS OF FLT3 BIOMEA FUSION, INC. 2025-05-01 US disclosed
CN-119528824-A 2-Oxo quinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2025-02-28 CN disclosed
CN-1780821-A Heterocyclic kinase inhibitors. ABBOTT LAB (US) 2006-05-31 CN disclosed
EP-1598349-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-23 EP disclosed
WO-2005090305-A1 5-AMINO-4-HYDROXY-7-(1H-INDOLMETHYL)-8-METHYLNONAMIDE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION SPEEDEL EXPERIMENTA AG (CH) 2005-09-29 WO disclosed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US disclosed
EP-1008383-A1 LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME KANEKA CORPORATION (JP) 2000-06-14 EP disclosed
EP-0010770-B1 4-PYRIDYL UREAS OR THIOUREAS SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND PLANT GROWTH REGULANTS CONTAINING THEM Shudo, Koichi, Prof. Dr. (JP) 1982-07-07 EP disclosed
US-4279639-A N-(2-Substituted-4-pyridyl)ureas and thioureas as well as plant growth regulators containing same, and method for using compounds as plant growth regulators Okamoto, Toshihiko (JP) 1981-07-21 US disclosed
EP-0010770-A1 4-Pyridyl ureas or thioureas substituted in position 2, process for their preparation and plant growth regulants containing them Shudo, Koichi, Prof. Dr. (JP) 1980-05-14 EP disclosed