SCHEMBL24029799

SCHEMBL24029799

CN(C)C(=O)N(C)CCNC(=O)C(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
CA14 Q9ULX7 2/20 0.37
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA7 P43166 1/20 0.34
CTSK P43235 4/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CKS1B P61024 1/20 0.33
SKP1 P63208 1/20 0.33
SKP2 Q13309 1/20 0.33
IDO1 P14902 1/20 0.33
EPHX1 P07099 1/20 0.31
CTSS P25774 1/20 0.31
CHRM2 P08172 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26553378 0.86 TDP1 (0.42) TDP1CA14MAOAMAOBMEN1
SCHEMBL24029801 0.84 TDP1 (0.50) TDP1CA14MAOAMAOBMEN1
SCHEMBL26553584 0.82 TDP1 (0.37) TDP1CA14MAOAMAOBMEN1
SCHEMBL26570547 0.78 TDP1 (0.36) TDP1CA14MAOAMAOBMEN1
SCHEMBL24897606 0.77 CTSK (0.36) TDP1CA14MAOAMAOBMEN1
SCHEMBL26551084 0.76 POLB (0.39) CA14CA1CA7CA2
SCHEMBL24029771 0.75 CHRM2 (0.34) TDP1CA14CTSSCHRM2CHRM4
SCHEMBL24029811 0.74 SIGMAR1 (0.49) MEN1KMT2AIDO1CTSS
SCHEMBL20543014 0.74 TDP1 (0.54) TDP1MAOAMAOBMEN1GAA
SCHEMBL19995511 0.74 TDP1 (0.50) TDP1CA14MAOAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
WO-2021227440-A1 A CLASS OF ARYL GLUCOSIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海喆邺生物科技有限公司 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SLC5A1, SLC5A2, SLC10A1 TDP1 3385/4885CA14 3396/4885MAOA 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.