SCHEMBL26570547

SCHEMBL26570547

C#CCN(C)CCNC(=O)C(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
CA14 Q9ULX7 2/20 0.34
MAOB P27338 5/20 0.34
MAOA P21397 2/20 0.33
KCNQ4 P56696 1/20 0.32
KCNQ5 Q9NR82 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA7 P43166 1/20 0.31
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31
CKS1B P61024 1/20 0.31
SKP1 P63208 1/20 0.31
SKP2 Q13309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24029771 0.88 CHRM2 (0.34) TDP1CA14CHRM2CHRM4CHRM5
SCHEMBL3250569 0.86 TDP1 (0.45) TDP1CA14MAOBMAOAKCNQ4
SCHEMBL24897606 0.86 CTSK (0.36) TDP1CA14MAOBMAOAMEN1
SCHEMBL26553378 0.82 TDP1 (0.42) TDP1CA14MAOBMAOAMEN1
SCHEMBL26553584 0.80 TDP1 (0.37) TDP1CA14MAOBMAOAMEN1
SCHEMBL26550945 0.78 MAOB (0.35) MAOBMAOA
SCHEMBL24029799 0.78 TDP1 (0.40) TDP1CA14MAOBMAOAMEN1
SCHEMBL24030147 0.77 CTSD (0.37) MEN1KMT2ACHRM2CHRM4CHRM5
SCHEMBL26571822 0.76 KCNQ4 (0.33) MAOBMAOAKCNQ4KCNQ5
SCHEMBL24029587 0.76 MAOB (0.34) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 US disclosed
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 US disclosed
US-20230331760-A1 ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331760-A1 ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG SLC5A1, SLC5A2, SLC10A1 TDP1 3644/4885CA14 3168/4885MAOB 1605/4885
US-20230365610-A1 Aryl Glucoside Derivative SLC5A1, SLC5A2, SLC10A1 TDP1 3449/4885CA14 3963/4885MAOB 1156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.