Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441219 | 0.94 | HDAC6 (0.59) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL1421044 | 0.88 | HDAC6 (0.64) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL24419731 | 0.86 | EPHX2 (0.55) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL15029019 | 0.85 | HDAC6 (0.72) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL16884347 | 0.84 | HDAC6 (0.56) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL15009111 | 0.84 | HDAC6 (0.50) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL1421158 | 0.84 | HDAC6 (0.74) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL15029094 | 0.82 | HDAC6 (0.72) | HDAC6ALDH1A1LMNAEPHX2CNR2 | |
| SCHEMBL21712145 | 0.81 | HDAC6 (1.00) | HDAC6CNR2HDAC8KMT2AMEN1 | |
| SCHEMBL18423583 | 0.81 | HDAC6 (0.70) | HDAC6ALDH1A1LMNAEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472271-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2025-11-18 | — | — | US | disclosed |
| EP-3931183-B1 | COMPOUNDS WITH FERROPTOSIS INDUCING ACTIVITY AND METHODS OF THEIR USE | FERRO THERAPEUTICS INC (US) | 2025-02-12 | — | — | EP | disclosed |
| EP-4397656-A2 | HDAC6 INHIBITORS AND IMAGING AGENTS | The General Hospital Corporation (US) | 2024-07-10 | — | — | EP | disclosed |
| US-20240148915-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2024-05-09 | — | — | US | disclosed |
| EP-3609864-B1 | HDAC6 INHIBITORS AND IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11890356-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-05-05 | — | — | US | disclosed |
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-05-05 | — | — | US | disclosed |
| CN-114008024-A | Compounds having iron death inducing activity and methods of using the same | 费罗治疗公司 | 2022-02-01 | — | — | CN | disclosed |
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | disclosed |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-09 | — | — | US | disclosed |
| WO-2013086131-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | US | disclosed |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | US | disclosed |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | US | disclosed |
| WO-2010043953-A2 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010043953-A2 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | HAVCR2, MAVS, ANTXR2 | HDAC6 1145/4885ALDH1A1 4453/4885LMNA 872/4885 |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | HAVCR2, MAVS, ANTXR2 | HDAC6 1240/4885ALDH1A1 4539/4885LMNA 705/4885 |
| US-20150191439-A1 | INHIBITORS TARGETING DRUG-RESISTANT INFLUENZA A | HAVCR2, HDLBP, HSP90B1 | HDAC6 581/4885ALDH1A1 3831/4885LMNA 1831/4885 |
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | HDAC6 510/4885ALDH1A1 1254/4885LMNA 2800/4885 |
| US-20240148915-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885ALDH1A1 2488/4885LMNA 1973/4885 |
| US-20110212943-A1 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | HDAC6 8/4885ALDH1A1 1442/4885LMNA 2309/4885 |
| US-12472271-B2 | HDAC6 inhibitors and imaging agents | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885ALDH1A1 2488/4885LMNA 1973/4885 |
| US-11890356-B2 | HDAC6 inhibitors and imaging agents | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885ALDH1A1 2488/4885LMNA 1973/4885 |
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885ALDH1A1 2488/4885LMNA 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.