Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295939 | 0.79 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3RAD52HTR2C | |
| SCHEMBL20684924 | 0.77 | HRH3 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22542020 | 0.77 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3RAD52ADRB1 | |
| SCHEMBL4025392 | 0.77 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3RAD52ADRB1 | |
| SCHEMBL22542046 | 0.77 | ADRB1 (0.52) | SLC6A2SLC6A4SLC6A3RAD52ADRB1 | |
| SCHEMBL24989412 | 0.76 | HRH3 (0.49) | SLC6A2SLC6A4SLC6A3RAD52HTR2C | |
| SCHEMBL22411659 | 0.75 | RAD52 (0.49) | SLC6A2SLC6A4SLC6A3RAD52WEE1 | |
| SCHEMBL5630967 | 0.75 | RAD52 (0.49) | SLC6A2SLC6A4SLC6A3RAD52WEE1 | |
| SCHEMBL5632812 | 0.75 | RAD52 (0.46) | SLC6A2SLC6A4SLC6A3RAD52GSK3B | |
| SCHEMBL335933 | 0.75 | HTR3A (0.50) | SLC6A2SLC6A4SLC6A3RAD52WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228248-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2021-11-18 | — | — | WO | disclosed |