Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801980 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1GFER | |
| SCHEMBL22801996 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1GFER | |
| SCHEMBL24030360 | 0.79 | SLC6A2 (0.42) | HTR2AHTR2CHTR2BRAD52SLC6A2 | |
| SCHEMBL28596325 | 0.78 | USP2 (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1473008 | 0.78 | USP2 (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5742221 | 0.78 | OPRD1 (0.46) | MAPTALDH1A1L3MBTL1RAD52SMN1; SMN2 | |
| SCHEMBL4040327 | 0.77 | ALDH1A1 (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22411659 | 0.77 | RAD52 (0.49) | MAPTKDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL5630967 | 0.77 | RAD52 (0.49) | MAPTKDM4EALDH1A1HTR2AHTR2C | |
| SCHEMBL25931364 | 0.77 | RAD52 (0.49) | MAPTKDM4EALDH1A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |