Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26010105 | 0.99 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL179184 | 0.92 | PLA2G2A (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1755425 | 0.91 | PLA2G2A (0.40) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL25784973 | 0.90 | PLA2G2A (0.42) | MEN1KMT2AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL15889121 | 0.90 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL21426315 | 0.88 | PLA2G2A (0.44) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL14052191 | 0.88 | MAOA (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL26753530 | 0.88 | GABRP (0.39) | PLA2G2APLA2G4A | |
| SCHEMBL10072123 | 0.88 | PLA2G2A (0.44) | MAPTMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL179189 | 0.87 | PLA2G2A (0.34) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021230133-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2021-11-18 | — | — | WO | disclosed |