Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405514 | 0.91 | ACHE (0.84) | ACHEBCHE | |
| Icopezil SCHEMBL194482 | 0.91 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL4512593 | 0.87 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL2402320 | 0.85 | ACHE (0.90) | ACHEBCHE | |
| Icopezil SCHEMBL2231222 | 0.85 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL3339253 | 0.85 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL8574448 | 0.84 | ACHE (0.59) | ACHEBCHE | |
| SCHEMBL27340198 | 0.84 | ACHE (0.59) | ACHEBCHE | |
| SCHEMBL220485 | 0.83 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL9276199 | 0.82 | ACHE (0.93) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951873-B1 | Methods for treating age-related behavioral disorders in companion animals | PFIZER INC. (US) | 2005-10-04 | — | — | US | claimed |
| EP-1050303-A2 | Methods and compositions for treating age-related behavioral disorders in companion animals | Pfizer Products Inc. (US) | 2000-11-08 | — | — | EP | claimed |
| US-20220265685-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2022-08-25 | — | — | US | disclosed |
| US-11160785-B2 | Methods and compositions for improving cognitive function | AGENEBIO INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20180015109-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY | 2018-01-18 | — | — | US | disclosed |
| US-20160271108-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | AGENEBIO, INC. | 2016-09-22 | — | — | US | disclosed |
| EP-2533645-B1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | UNIV JOHNS HOPKINS (US) | 2016-07-27 | — | — | EP | disclosed |
| US-20110212928-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-09-01 | — | — | US | disclosed |
| US-6951873-B1 | Methods for treating age-related behavioral disorders in companion animals | PFIZER INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-6498255-B2 | CHOLINESTERASE INHIBITORS; COGNITION ACTIVATORS; ALZHEIMER'S DISEASE; E.G., 3-(2-(1-(PHENYLMETHYL)-4-PIPERIDINYL)ETHYL)-1,2-BENZISOXAZOLE | PFIZER INC. | 2002-12-24 | — | — | US | disclosed |
| EP-1050303-A2 | Methods and compositions for treating age-related behavioral disorders in companion animals | Pfizer Products Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271108-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE2, BACE1, GRIN2A | ACHE 4/4885BCHE 29/4885 |
| US-11160785-B2 | Methods and compositions for improving cognitive function | BACE2, BACE1, GRIN2A | ACHE 4/4885BCHE 29/4885 |
| US-20180015109-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE1, BACE2, ACHE | ACHE 3/4885BCHE 47/4885 |
| US-20220265685-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE1, BACE2, ACHE | ACHE 3/4885BCHE 47/4885 |
| US-20110212928-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | BACE1, BACE2, ACHE | ACHE 3/4885BCHE 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.