SCHEMBL24037211

SCHEMBL24037211

O=C1C=C(O)[C@@H]([C@@H](O)CO)O1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MANBA O00462 1/20 0.38
THRB P10828 1/20 0.38
HIF1A Q16665 1/20 0.38
TYR P14679 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15976337 1.00 LMNA (0.50) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL28229704 1.00 LMNA (0.50) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL15827805 0.79 LMNA (0.49) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL19140901 0.74 JUN (0.36)
SCHEMBL18614890 0.72
SCHEMBL1797707 0.67
Ascorbic Acid SCHEMBL11981759 0.67 MAPT (1.00) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL3700961 0.67 LMNA (0.56) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL4430 0.67 LMNA (0.56) LMNAMAPTL3MBTL1MANBATHRB
Ascorbic Acid SCHEMBL21114349 0.67 MAPT (1.00) LMNAMAPTL3MBTL1MANBATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957378-A Renaturation method of hydrophobic inclusion body antigen protein 深圳重链生物科技有限公司 2022-08-30 CN claimed
CN-118159549-A Immunomodulators 百时美施贵宝公司 2024-06-07 CN disclosed
CN-114957378-A Renaturation method of hydrophobic inclusion body antigen protein 深圳重链生物科技有限公司 2022-08-30 CN disclosed
WO-2021231829-A1 HIGH BIO-RENEWABLE CONTENT INKS AND RESINS SUN CHEMICAL CORPORATION (US) 2021-11-18 WO disclosed