SCHEMBL24037809

SCHEMBL24037809

N#Cc1ccc2nc(-c3ccc(-c4ccc5cc(-c6ccc(-c7cc(C(F)(F)F)cc(C(F)(F)F)c7)cc6)ccc5c4)cc3)oc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 2/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
CETP P11597 8/20 0.42
DGAT1 O75907 1/20 0.41
SOAT1 P35610 1/20 0.41
KCNH2 Q12809 1/20 0.41
TLR9 Q9NR96 1/20 0.41
CEPT1 Q9Y6K0 1/20 0.41
KIF11 P52732 1/20 0.40
CSNK1D P48730 1/20 0.40
CSNK1G2 P78368 1/20 0.40
HDAC6 Q9UBN7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24038137 0.94 PGR (0.42) GPR119ESR1ESR2CETPDGAT1
SCHEMBL24037811 0.93 KIF11 (0.49) GPR119ESR1ESR2CETPDGAT1
SCHEMBL18935925 0.87 KIF11 (0.51) GPR119ESR1ESR2CETPDGAT1
SCHEMBL24038264 0.87 ESR1 (0.51) GPR119ESR1ESR2CETPCEPT1
SCHEMBL24038202 0.85 ESR1 (0.45) GPR119ESR1ESR2CETPTLR9
SCHEMBL24038201 0.84 HDAC6 (0.48) GPR119ESR1ESR2CETPCEPT1
SCHEMBL24038144 0.84 ESR1 (0.44) GPR119ESR1ESR2CETPCEPT1
SCHEMBL24038265 0.83 GPR119 (0.46) GPR119ESR1ESR2CETPCEPT1
SCHEMBL24038196 0.83 ESR1 (0.46) GPR119ESR1ESR2TLR9CEPT1
SCHEMBL24038396 0.82 NPC1 (0.56) GPR119ESR1ESR2TLR9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021230512-A1 BENZAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-11-18 WO disclosed