SCHEMBL24038121

SCHEMBL24038121

Bc1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRA P19793 6/20 0.44
RXRB P28702 6/20 0.44
RXRG P48443 5/20 0.44
CES2 O00748 1/20 0.39
IDO1 P14902 2/20 0.35
IKBKB O14920 1/20 0.35
XPO1 O14980 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
ADRB1 P08588 1/20 0.32
MAPT P10636 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13866628 0.87 RXRA (0.52) RXRARXRBRXRGCES2IDO1
SCHEMBL3684529 0.84 CES2 (0.46) RXRARXRBRXRGCES2IDO1
SCHEMBL9482063 0.84 RXRA (0.54) RXRARXRBRXRGCES2IDO1
Water SCHEMBL27788452 0.81 CES2 (0.44) RXRARXRBRXRGCES2IDO1
SCHEMBL28802521 0.81 CES2 (0.44) RXRARXRBRXRGCES2IDO1
SCHEMBL29136201 0.81 CES2 (0.44) RXRARXRBRXRGCES2IDO1
SCHEMBL24038365 0.81 RXRA (0.55) RXRARXRBRXRGCES2
SCHEMBL24038287 0.81 RXRA (0.55) RXRARXRBRXRGCES2
Hydrazine SCHEMBL2139143 0.78 RXRA (0.45) RXRARXRBRXRGCES2IDO1
SCHEMBL19270461 0.78 CES2 (0.40) RXRARXRBRXRGCES2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021230512-A1 BENZAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-11-18 WO disclosed