Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684529 | 0.97 | CES2 (0.46) | CES2IDO1XPO1ADRB1TSHR | |
| SCHEMBL28802521 | 0.94 | CES2 (0.44) | CES2IDO1XPO1ADRB1TSHR | |
| Water SCHEMBL27788452 | 0.94 | CES2 (0.44) | CES2IDO1XPO1ADRB1TSHR | |
| SCHEMBL24038121 | 0.81 | RXRA (0.44) | CES2IDO1XPO1ADRB1RXRA | |
| SCHEMBL440959 | 0.80 | CES2 (0.58) | CES2IDO1XPO1ADRB1TSHR | |
| SCHEMBL15943174 | 0.79 | RAPGEF4 (0.41) | CES2IDO1TSHRALDH1A1RAPGEF4 | |
| SCHEMBL14303165 | 0.79 | CES2 (0.33) | CES2IDO1 | |
| SCHEMBL10046161 | 0.79 | TSHR (0.46) | CES2IDO1TSHRALDH1A1MAPT | |
| SCHEMBL2665686 | 0.79 | RAPGEF4 (0.42) | CES2XPO1MAPTRAPGEF4HDAC3 | |
| Tromethamine SCHEMBL7762678 | 0.78 | LMNA (0.40) | CES2IDO1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003919-B | Multifunctional macromolecular anti-aging agent and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2024-05-31 | — | — | CN | claimed |
| CN-117003919-A | Multifunctional macromolecular anti-aging agent and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2023-11-07 | — | — | CN | claimed |
| CN-117003919-B | Multifunctional macromolecular anti-aging agent and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2024-05-31 | — | — | CN | disclosed |
| CN-117003919-A | Multifunctional macromolecular anti-aging agent and preparation method and application thereof | 广东省科学院生物与医学工程研究所 | 2023-11-07 | — | — | CN | disclosed |