Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25725831 | 0.68 | TBXAS1 (0.39) | ALDH1A1 | |
| SCHEMBL276216 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL2008459 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL20955977 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL24097278 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL4566858 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1TSHRKDM4ENPC1 | |
| SCHEMBL276215 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL2008456 | 0.67 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4ENPC1POLB | |
| SCHEMBL30977402 | 0.65 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL29229894 | 0.65 | ALDH1A1 (0.92) | ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229302-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-11-18 | — | — | WO | disclosed |