Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366658 | 0.80 | ACP3 (0.42) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL28681045 | 0.80 | ACP3 (0.42) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL10618424 | 0.77 | HPGD (0.52) | AOC3LMNA | |
| SCHEMBL867222 | 0.74 | LMNA (0.57) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL15918132 | 0.74 | CASP1 (0.59) | — | |
| SCHEMBL3482675 | 0.74 | LMNA (0.57) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL3482807 | 0.74 | LMNA (0.57) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL28825411 | 0.73 | MAPT (0.44) | GLSMEN1KMT2A | |
| SCHEMBL19390817 | 0.73 | ACP3 (0.48) | ADRB2ADRB1ADRB3ACP3SLC6A2 | |
| SCHEMBL12907075 | 0.73 | ACP3 (0.46) | ADRB2ADRB1ADRB3ACP3GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231784-A1 | PERK INHIBITING IMIDAZOLOPYRAZINE COMPOUNDS | HIBERCELL, INC. (US) | 2021-11-18 | — | — | WO | disclosed |