SCHEMBL3482675

SCHEMBL3482675

CC[C@@H](O)c1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
ADRB1 P08588 5/20 0.50
ADRB3 P13945 5/20 0.50
ADRB2 P07550 3/20 0.50
SLC2A1 P11166 2/20 0.49
IDO1 P14902 2/20 0.44
ACP3 P15309 1/20 0.43
TP53 P04637 1/20 0.43
AOC3 Q16853 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482807 1.00 LMNA (0.57) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL867222 1.00 LMNA (0.57) LMNAADRB1ADRB3ADRB2SLC2A1
Dimethylamine SCHEMBL27944752 0.94 LMNA (0.52) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL11595350 0.85 LMNA (0.70) LMNAADRB1ADRB3ADRB2AOC3
SCHEMBL13849942 0.85 ADRB1 (0.48) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL6690481 0.85 ADRB1 (0.48) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL13849930 0.85 ADRB1 (0.48) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL14402491 0.85 ADRB1 (0.48) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL1154749 0.83 ADRB3 (0.49) LMNAADRB1ADRB3ADRB2SLC2A1
SCHEMBL2879198 0.83 ADRB3 (0.49) LMNAADRB1ADRB3ADRB2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118771958-A Preparation method of R- (+) -3-chloropropanol 山东省药学科学院 2024-10-15 CN claimed
CN-112980895-B Enzymatic synthesis method of (R) -3-chloropropanol 宿迁阿尔法科技有限公司 2023-09-26 CN claimed
CN-112980895-A Enzymatic synthesis method of (R) -3-chlorophenylpropanol 宿迁阿尔法科技有限公司 2021-06-18 CN claimed
CN-121159365-A Method for preparing high-purity R- (+) -3-chloropropanol monocyclone 天方药业有限公司 2025-12-19 CN disclosed
CN-118685463-B Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies 杭州微远生物科技有限公司 2025-04-25 CN disclosed
CN-118879823-A Synthesis method of (R) -3-halogenated phenylpropanol 四川新迪生物制药有限公司 2024-11-01 CN disclosed
CN-118771958-A Preparation method of R- (+) -3-chloropropanol 山东省药学科学院 2024-10-15 CN disclosed
CN-118685463-A Dapoxetine chiral intermediates of statins enzymatic synthesis of bodies 杭州微远生物科技有限公司 2024-09-24 CN disclosed
CN-118666651-A Dapoxetine chirality Process for the preparation of intermediates 济南鸿湾生物技术有限公司 2024-09-20 CN disclosed
CN-112980895-B Enzymatic synthesis method of (R) -3-chloropropanol 宿迁阿尔法科技有限公司 2023-09-26 CN disclosed
CN-116589367-A Preparation method of dapoxetine hydrochloride 济南鸿湾生物技术有限公司 2023-08-15 CN disclosed
US-20030082623-A1 DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof H. LUNDBECK A/S (DK) 2003-05-01 US disclosed
US-20030077701-A1 DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof H. LUNDBECK A/S (DK) 2003-04-24 US disclosed
WO-2003004027-A1 SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2003-01-16 WO disclosed
EP-1246847-A2 DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF Synaptic Pharmaceutical Corporation (US) 2002-10-09 EP disclosed
WO-2002002744-A2 DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2002-01-10 WO disclosed
WO-2000020386-A1 STANNANE SYNTHESIS OF PROSTANOIDS ALCON LABORATORIES, INC. (US) 2000-04-13 WO disclosed
EP-0743940-A1 NEW COMPOUNDS WITH ANALGESIC AND LOCAL ANAESTHETIC EFFECT Astra Aktiebolag (SE) 1996-11-27 EP disclosed
WO-1995021821-A1 NEW COMPOUNDS WITH ANALGESIC AND LOCAL ANAESTHETIC EFFECT ASTRA AKTIEBOLAG (SE) 1995-08-17 WO disclosed
US-4918246-A REDUCING HALOKETONE WITH DIISOPINOCAMPHEYLBORANE ALDRICH CHEMICAL COMPANY, INC. (US) 1990-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082623-A1 DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof MCHR1, MCHR2, MC1R LMNA 2573/4885ADRB1 468/4885ADRB3 555/4885
US-20030077701-A1 DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof MCHR1, MCHR2, MC1R LMNA 2573/4885ADRB1 468/4885ADRB3 555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.