Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 5/20 | 0.45 |
| ▸ | PNMT | P11086 | 2/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30090302 | 0.88 | PARP1 (0.47) | PARP1PARP2PARP3ASIC3HTR6 | |
| SCHEMBL24038913 | 0.88 | NOTUM (0.47) | DRD2DRD3NOTUMHTR6KDM4E | |
| SCHEMBL31599425 | 0.79 | DRD2 (0.45) | DRD2DRD3NOTUMKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL25274822 | 0.76 | PDK2 (0.44) | PARP1PARP2PARP3NOTUMKDM4E | |
| Trifluoroacetic Acid SCHEMBL30090423 | 0.76 | PDK2 (0.44) | PARP1PARP2PARP3NOTUMKDM4E | |
| SCHEMBL28324452 | 0.73 | CYP11B2 (0.46) | DRD2DRD3NOTUMKDM4EALDH1A1 | |
| SCHEMBL5210453 | 0.70 | KDM4E (0.40) | DRD2DRD3NOTUMHTR6KDM4E | |
| SCHEMBL25406974 | 0.69 | ASIC3 (0.58) | ASIC3PNMTCD44MAOBDRD2 | |
| SCHEMBL4171450 | 0.69 | ASIC3 (0.51) | ASIC3PNMTCD44MAOBDRD2 | |
| SCHEMBL4341894 | 0.69 | NOTUM (0.78) | DRD2DRD3NOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192677-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2023-06-22 | — | — | US | disclosed |
| US-20230192677-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2023-06-22 | — | — | US | disclosed |
| US-20230192677-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2023-06-22 | — | — | US | disclosed |
| EP-4149924-A1 | CYP11A1 INHIBITORS | Orion Corporation (FI) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551831-A | CYP11A1 inhibitor | 奥赖恩公司 | 2022-12-30 | — | — | CN | disclosed |
| WO-2021229152-A1 | CYP11A1 INHIBITORS | ORION CORPORATION (FI) | 2021-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192677-A1 | CYP11A1 INHIBITORS | CYP11B1, CYP11B2, CYP17A1 | PARP1 2342/4885PARP2 2913/4885PARP3 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.