Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.49 |
| ▸ | TK2 | O00142 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ATG7 | O95352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30179160 | 0.91 | ADK (0.52) | HIF1AADKDNMT1ADRB1FPR2 | |
| SCHEMBL16378847 | 0.87 | ADK (0.54) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL17106694 | 0.87 | ADK (0.54) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL23019063 | 0.87 | ADK (0.54) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL23745928 | 0.85 | ADK (0.54) | HIF1AADKDNMT1ADRB1FPR2 | |
| SCHEMBL24127868 | 0.85 | ADK (0.54) | HIF1AADKDNMT1ADRB1FPR2 | |
| SCHEMBL18490333 | 0.84 | ADK (0.52) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL20419182 | 0.84 | PRMT5 (0.59) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL17114379 | 0.84 | PRMT5 (0.59) | HIF1AADKDNMT1ADRB1PNP | |
| SCHEMBL15740255 | 0.84 | ADK (0.56) | HIF1AADKDNMT1ADRB1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180522-B2 | Disulfide-linked reversible terminators | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2021-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180522-B2 | Disulfide-linked reversible terminators | RNGTT, NSUN3, NSUN2 | HIF1A 4640/4885ADK 1213/4885DNMT1 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.