⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24040378 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL20144565 | 0.72 | SIRT5 (0.32) | — | |
| SCHEMBL20144536 | 0.69 | KDM4E (0.35) | — | |
| SCHEMBL24812501 | 0.65 | KMT2A (0.50) | — | |
| SCHEMBL19277701 | 0.65 | KMT2A (0.50) | — | |
| SCHEMBL20144535 | 0.64 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL27310599 | 0.64 | MEN1 (0.38) | — | |
| SCHEMBL8256099 | 0.63 | GLP1R (0.47) | — | |
| SCHEMBL18855041 | 0.60 | KMT2A (0.47) | — | |
| SCHEMBL20144537 | 0.60 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11179467-B2 | Exenatide modifier and use thereof | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2021-11-23 | — | — | US | disclosed |