Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041787 | 0.89 | BCHE (0.45) | MAOBKCNH2BCHESIGMAR1 | |
| SCHEMBL4568878 | 0.81 | PPARA (0.58) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL20131148 | 0.81 | IDO1 (0.55) | MAOADRD3KCNH2SIGMAR1 | |
| SCHEMBL8757293 | 0.80 | CA1 (0.44) | — | |
| SCHEMBL4568874 | 0.80 | PPARG (0.57) | BCHEFFAR1PPARGPPARA | |
| SCHEMBL24041797 | 0.80 | MAOB (0.52) | MAOBKCNH2BCHEFFAR1SIGMAR1 | |
| SCHEMBL24041798 | 0.80 | CHRNA7 (0.50) | DRD2DRD4DRD3KCNH2FFAR1 | |
| SCHEMBL2207165 | 0.78 | MAOA (0.53) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL8862908 | 0.78 | MAOA (0.50) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL24041871 | 0.78 | CYP4F2 (0.71) | MAOAMAOBDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |