Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | AGXT | P21549 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723511 | 0.92 | TAAR1 (0.77) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL30080050 | 0.92 | TAAR1 (0.77) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL4060273 | 0.90 | TAAR1 (0.69) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL22858341 | 0.89 | TAAR1 (0.62) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL27772539 | 0.87 | GABRA1 (0.63) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL3364226 | 0.87 | CYP19A1 (0.71) | TAAR1CHRM2CHRM1CHRM3MAOB | |
| SCHEMBL13946245 | 0.87 | TAAR1 (0.61) | TAAR1CHRM2CHRM1CHRM3MAOB | |
| SCHEMBL1975466 | 0.86 | TAAR1 (0.69) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL22402810 | 0.85 | TUBB4A (0.51) | TAAR1ABCB1CHRM2CHRM1CHRM3 | |
| SCHEMBL7336705 | 0.84 | TAAR1 (0.67) | TAAR1CHRM2CHRM1CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |