SCHEMBL24044019

SCHEMBL24044019

O=S(=O)(c1ccc(Br)cc1)c1ccc(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 5/20 0.42
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
CA2 P00918 6/20 0.40
CA1 P00915 5/20 0.40
CA12 O43570 4/20 0.38
HTR6 P50406 3/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.37
PTGS2 P35354 1/20 0.37
MMP2 P08253 2/20 0.36
MMP1 P03956 1/20 0.36
MMP3 P08254 1/20 0.36
MMP7 P09237 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291364 0.93 HTR6 (0.42) CA9ALDH1A1CA2CA1CA12
SCHEMBL18083035 0.89 KDM4E (0.47) CA9ALDH1A1CA2CA1CA12
SCHEMBL31122338 0.89 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2
SCHEMBL30045167 0.89 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2
SCHEMBL17742564 0.89 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2
SCHEMBL2597529 0.89 ALDH1A1 (0.52) ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2
SCHEMBL16664362 0.86 KDM4E (0.45) CA9ALDH1A1CA2CA1CA12
SCHEMBL19238793 0.86 KDM4E (0.51) CA9ALDH1A1CA2CA1CA12
SCHEMBL17109696 0.86 KDM4E (0.46) CA9CA2CA1CA12HTR6
SCHEMBL17739641 0.86 L3MBTL1 (0.46) CA9ALDH1A1MAPK1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210363416-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT AND SYNTHESIZING METHOD THEREOF WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210363416-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT AND SYNTHESIZING METHOD THEREOF HSF1, TBCA, CPSF7 CA9 1773/4885ALDH1A1 733/4885MAPK1 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.