Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045243 | 0.84 | MEN1 (0.66) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045244 | 0.84 | MEN1 (0.66) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045250 | 0.83 | MEN1 (0.65) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045249 | 0.82 | MEN1 (0.64) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045247 | 0.82 | MEN1 (0.69) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045245 | 0.80 | MEN1 (0.69) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045248 | 0.79 | DUSP3 (0.82) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL24045246 | 0.78 | MEN1 (0.64) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL25104837 | 0.77 | MEN1 (0.72) | MEN1KMT2ADUSP3PTPN5PTPN11 | |
| SCHEMBL26687625 | 0.77 | DUSP3 (1.00) | MEN1KMT2ADUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-26 | — | — | US | disclosed |
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-26 | — | — | US | disclosed |
| US-11591304-B2 | SLC26A3 inhibitors and use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210363123-A1 | SLC26A3 INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339878-A1 | SLC26A3 INHIBITORS AND USE THEREOF | SLC26A3, SLC10A2, SLC10A6 | MEN1 4700/4885KMT2A 4380/4885DUSP3 1509/4885 |
| US-20210363123-A1 | SLC26A3 INHIBITORS AND USE THEREOF | SLC26A3, SLC10A2, SLC10A6 | MEN1 4646/4885KMT2A 4076/4885DUSP3 1349/4885 |
| US-11591304-B2 | SLC26A3 inhibitors and use thereof | SLC26A3, SLC10A2, SLC10A6 | MEN1 4646/4885KMT2A 4076/4885DUSP3 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.