Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30930946 | 0.79 | HPGD (0.43) | ALDH1A1PDK2HPGDF10PRSS1 | |
| SCHEMBL18955154 | 0.78 | PIP4K2A (0.51) | ALDH1A1AKR1C3HPGDF10PRSS1 | |
| SCHEMBL3666589 | 0.77 | LMNA (0.59) | ALDH1A1AKR1C3HPGDF10USP2 | |
| SCHEMBL76559 | 0.77 | ALDH1A1 (0.59) | ALDH1A1AKR1C3HPGDGFERLMNA | |
| SCHEMBL27409503 | 0.77 | ALDH1A1 (0.59) | ALDH1A1AKR1C3HPGDGFERLMNA | |
| SCHEMBL2728631 | 0.76 | LMNA (0.58) | ALDH1A1AKR1C3HPGDF10USP2 | |
| SCHEMBL26779861 | 0.76 | ALDH1A1 (0.64) | ALDH1A1AKR1C3HPGDGFERLMNA | |
| SCHEMBL1626841 | 0.76 | ALDH1A1 (0.58) | ALDH1A1AKR1C3HPGDGFERLMNA | |
| SCHEMBL329316 | 0.76 | ALDH1A1 (0.58) | ALDH1A1AKR1C3HPGDGFERLMNA | |
| Hydrochloric Acid SCHEMBL7459714 | 0.76 | ALDH1A1 (0.58) | ALDH1A1AKR1C3HPGDGFERLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |