Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.51 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582035 | 0.84 | NAAA (0.43) | PIP4K2APIP4K2CF10PRSS1PRSS2 | |
| SCHEMBL24045765 | 0.78 | FPR2 (0.48) | F10PRSS1PRSS2PRSS3AKR1C3 | |
| SCHEMBL18955219 | 0.76 | FPR1 (0.46) | F10PRSS1PRSS2PRSS3AKR1C3 | |
| SCHEMBL22553839 | 0.75 | NPC1 (0.48) | PIP4K2APIP4K2CF10PRSS1PRSS2 | |
| SCHEMBL22554094 | 0.75 | PIP4K2A (0.43) | PIP4K2APIP4K2CF10PRSS1PRSS2 | |
| SCHEMBL30730861 | 0.75 | PIP4K2A (0.43) | PIP4K2APIP4K2CF10PRSS1PRSS2 | |
| SCHEMBL24045800 | 0.74 | CYP11B1 (0.55) | MKNK1MKNK2GAAALDH1A1 | |
| SCHEMBL22575149 | 0.74 | PRKAB2 (0.47) | F10PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL24045801 | 0.73 | MEN1 (0.53) | MEN1KMT2ALMNAHPGD | |
| SCHEMBL609322 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AAKR1C3LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-3414227-A1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017100390-A1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-06-15 | — | — | WO | disclosed |