Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 1.00 |
| ▸ | NOS1 | P29475 | 6/20 | 0.75 |
| ▸ | HGFAC | Q04756 | 3/20 | 0.67 |
| ▸ | NOS3 | P29474 | 4/20 | 0.66 |
| ▸ | NOS2 | P35228 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7258089 | 0.98 | PLAU (0.96) | PLAUNOS1HGFACNOS3NOS2 | |
| Nitric Acid SCHEMBL3860515 | 0.96 | PLAU (0.92) | PLAUNOS1HGFACNOS3NOS2 | |
| SCHEMBL29358345 | 0.82 | HGFAC (1.00) | PLAUHGFACF2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL30117920 | 0.81 | HGFAC (0.97) | PLAUHGFACF2PRSS1PRSS2 | |
| SCHEMBL16470336 | 0.78 | PLAU (0.64) | PLAUNOS1NOS3NOS2GRIN2D | |
| SCHEMBL4869749 | 0.78 | PLAU (0.64) | PLAUNOS1HGFACNOS3NOS2 | |
| Iodide SCHEMBL8618701 | 0.78 | NOS1 (1.00) | PLAUNOS1HGFACNOS3NOS2 | |
| Nitric Acid SCHEMBL6033862 | 0.78 | CA12 (0.72) | PLAUNOS1HGFACNOS3NOS2 | |
| SCHEMBL3812219 | 0.77 | HTR3E (0.77) | PLAUHGFACPOLBF2PRSS1 | |
| Hydrochloric Acid SCHEMBL15527609 | 0.77 | NOS1 (0.63) | PLAUNOS1NOS3NOS2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517852-B1 | TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS | OREGON STATE (US) | 2002-07-10 | — | — | EP | claimed |
| EP-3621952-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | AlzChem Trostberg GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018210633-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | ALZCHEM TROSTBERG GMBH (DE) | 2018-11-22 | — | — | WO | disclosed |
| US-8753841-B2 | Enzyme that catalyzes a peptide-forming reaction from a carboxy component and an amine component, microbe producing the same, and a method of producing a dipeptide using the enzyme or microbe | AJINOMOTO CO., INC. (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20130122544-A1 | ENZYME THAT CATALYZES A PEPTIDE-FORMING REACTION FROM A CARBOXY COMPONENT AND AN AMINE COMPONENT, MICROBE PRODUCING THE SAME, AND A METHOD OF PRODUCING A DIPEPTIDE USING THE ENZYME OR MICROBE | AJINOMOTO CO., INC. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-8389241-B2 | Enzyme that catalyzes a peptide-forming reaction from a carboxy component and an amine component, microbe producing the same, and a method of producing a dipeptide using the enzyme or microbe | AJINOMOTO CO., INC. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20130011873-A1 | ENZYME THAT CATALYZES A PEPTIDE-FORMING REACTION FROM A CARBOXY COMPONENT AND AN AMINE COMPONENT, MICROBE PRODUCING THE SAME, AND A METHOD OF PRODUCING A DIPEPTIDE USING THE ENZYME OR MICROBE | AJINOMOTO CO., INC. (JP) | 2013-01-10 | — | — | US | disclosed |
| US-8329428-B2 | Enzyme that catalyzes a peptide-forming reaction from a carboxy component and an amine component, microbe producing the same, and a method of producing a dipeptide using the enzyme or microbe | AJINOMOTO CO., INC. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120003693-A1 | NOVEL PEPTIDE-FORMING ENZYME GENE | AJINOMOTO CO., INC. (JP) | 2012-01-05 | — | — | US | disclosed |
| US-8039232-B2 | Method for producing a dipeptide | AJINOMOTO CO., INC. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7338780-B2 | Method for producing tripeptides and/or peptides longer than tripeptides | AJINOMOTO CO., INC. (JP) | 2008-03-04 | — | — | US | disclosed |
| US-20080050773-A1 | NOVEL PEPTIDE-FORMING ENZYME GENE | AJINOMOTO CO., INC. (JP) | 2008-02-28 | — | — | US | disclosed |
| US-7288389-B2 | Peptide-forming enzyme gene | AJINOMOTO CO., INC. (JP) | 2007-10-30 | — | — | US | disclosed |
| US-20050032187-A1 | Novel peptide-forming enzyme, microbe producing the enzyme and method for producing peptide using them | AJINOMOTO CO., INC. (JP) | 2005-02-10 | — | — | US | disclosed |
| US-20050032154-A1 | Method for producing tripeptides and/or peptides longer than tripeptides | AJINOMOTO CO., INC. (JP) | 2005-02-10 | — | — | US | disclosed |
| US-20050019864-A1 | Novel peptide-forming enzyme gene | AJINOMOTO CO., INC. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1228058-A4 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-02-12 | — | — | EP | disclosed |
| EP-1228058-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001029023-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-04-26 | — | — | WO | disclosed |
| EP-0353218-A2 | Method of producing lysplasminogen | IMMUNO Aktiengesellschaft (AT) | 1990-01-31 | — | — | EP | disclosed |