SCHEMBL29358345

SCHEMBL29358345

NC(N)=Nc1ccc(C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HGFAC Q04756 5/20 1.00
PRSS1 P07477 11/20 0.75
F2 P00734 4/20 0.75
PRSS2 P07478 4/20 0.75
PRSS3 P35030 4/20 0.75
PKM P14618 1/20 0.68
KMT2A Q03164 1/20 0.68
PLAU P00749 1/20 0.67
ACR P10323 8/20 0.66
PLG P00747 1/20 0.65
TMPRSS15 P98073 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30117920 0.99 HGFAC (0.97) HGFACPRSS1F2PRSS2PRSS3
SCHEMBL10636579 0.85 KMT2A (0.84) HGFACPKMKMT2A
SCHEMBL542043 0.85 KMT2A (0.84) HGFACPKMKMT2A
SCHEMBL18434657 0.85 KMT2A (0.84) HGFACPKMKMT2A
SCHEMBL4951809 0.85 KMT2A (0.84) HGFACPKMKMT2A
SCHEMBL240459 0.82 PLAU (1.00) HGFACPRSS1F2PRSS2PRSS3
SCHEMBL29029504 0.81 KMT2A (1.00) HGFACPRSS1F2PRSS2PRSS3
SCHEMBL27462144 0.81 HGFAC (0.67) HGFACPRSS1F2PRSS2PRSS3
SCHEMBL12489991 0.81 PKM (0.77) HGFACPKMKMT2A
SCHEMBL16375430 0.81 KMT2A (0.77) HGFACPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240177562-A1 Detection of Possible Problem Gambling Behaviour Mindway Al ApS (DK) 2024-05-30 US claimed
US-11893854-B2 Detection of possible problem gambling behaviour MINDWAY AI ApS (DK) 2024-02-06 US claimed
US-20220028213-A1 Detection of Possible Problem Gambling Behaviour MINDWAY AI ApS (DK) 2022-01-27 US claimed
US-20260098080-A1 A MODIFIED PROTEIN SCAFFOLD AND USE THEREOF EVOLVERITAS BIOTECHNOLÓGIAI KORLÁTOLT FELELOSSÉGU TÁRSASÁG (HU) 2026-04-09 US disclosed
EP-4594347-A2 A MODIFIED PROTEIN SCAFFOLD AND USE THEREOF Evolveritas Biotechnologiai Korlatolt Felelossegu Tarsasag (HU) 2025-08-06 EP disclosed
CN-119968388-A Modified protein scaffold and uses thereof 爱沃利塔斯生物技术有限责任公司 2025-05-09 CN disclosed
US-20240228665-A1 METHODS FOR TREATING CONDITIONS ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION OMEROS CORPORATION 2024-07-11 US disclosed
US-20240177562-A1 Detection of Possible Problem Gambling Behaviour Mindway Al ApS (DK) 2024-05-30 US disclosed
WO-2024069200-A2 A MODIFIED PROTEIN SCAFFOLD AND USE THEREOF EVOLVERITAS BIOTECHNOLÓGIAI KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) 2024-04-04 WO disclosed
US-20240076408-A1 METHODS FOR TREATING CONDITIONS ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION OMEROS CORPORATION 2024-03-07 US disclosed
US-11893854-B2 Detection of possible problem gambling behaviour MINDWAY AI ApS (DK) 2024-02-06 US disclosed
US-11884742-B2 Methods for treating conditions associated with MASP-2 dependent complement activation OMEROS CORPORATION (US) 2024-01-30 US disclosed
US-20230391889-A1 Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation OMEROS CORPORATION 2023-12-07 US disclosed
CN-117057287-A Sense amplifier, sensitivity enhancement method thereof, memory and electronic equipment 成都海光微电子技术有限公司 2023-11-14 CN disclosed
WO-2023099927-A1 METHOD FOR THE PREPARATION OF A RECOMBINANT TYPE II TRANSMEMBRANE PROTEASE SERINE FRAGMENT, SAID FRAGMENT, AND ITS USE EVOLVERITAS BIOTECHNOLÓGIAI KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) 2023-06-08 WO disclosed
US-20220028213-A1 Detection of Possible Problem Gambling Behaviour MINDWAY AI ApS (DK) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098080-A1 A MODIFIED PROTEIN SCAFFOLD AND USE THEREOF MLX, HAX1, TPX2 HGFAC 164/4885PRSS1 1278/4885F2 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.