Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | ALDH1A3 | P47895 | 7/20 | 0.79 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691409 | 0.89 | RAB9A (1.00) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL13325769 | 0.88 | ALDH1A3 (1.00) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL16246713 | 0.88 | ALDH1A3 (1.00) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL1664803 | 0.84 | RAB9A (0.83) | RAB9ANPC1ALDH1A1ALDH1A3APP | |
| SCHEMBL13217820 | 0.83 | RAB9A (0.81) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL13325716 | 0.83 | RAB9A (0.81) | RAB9ANPC1ALDH1A1ALDH1A3APP | |
| SCHEMBL5775919 | 0.83 | RAB9A (0.81) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL6483368 | 0.83 | RAB9A (0.74) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL13325714 | 0.82 | RAB9A (0.69) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL31683146 | 0.82 | RAB9A (0.69) | RAB9ANPC1ALDH1A1ALDH1A3ALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812530-A | Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system | 中国科学院大连化学物理研究所 | 2024-10-22 | — | — | CN | claimed |
| CN-118812530-A | Method for preparing imidazole pyridine compound by catalyzing lignin and model compound by Pd/C bi-component system | 中国科学院大连化学物理研究所 | 2024-10-22 | — | — | CN | disclosed |
| CN-114892187-B | Method for electrochemically synthesizing imidazole polycyclic aromatic compounds | 南京工业大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114892187-A | Method for electrochemically synthesizing imidazole polycyclic aromatic compounds | 南京工业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-113735852-A | Convenient Michal addition reaction of imidazole [1,2-a ] pyridine compounds | 桂林理工大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-110590774-B | Trifluoromethyl imidazole condensed ring compound and preparation method thereof | 河南中医药大学 | 2020-09-08 | — | — | CN | disclosed |
| CN-110590774-A | Trifluoromethyl imidazole condensed ring compound and preparation method thereof | 河南中医药大学 | 2019-12-20 | — | — | CN | disclosed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| US-7714319-B2 | Organic thin film transistor | IDEMITSU KOSAN CO., LTD. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20070120111-A1 | Organic thin film transistor | IDEMITSU KOSAN CO., LTD. (JP) | 2007-05-31 | — | — | US | disclosed |
| WO-2007008541-A2 | CELLULAR CHOLESTEROL ABSORPTION MODIFIERS | KALYPSYS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | RAB9A 1787/4885NPC1 147/4885ALDH1A1 1577/4885 |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | RAB9A 2150/4885NPC1 1540/4885ALDH1A1 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.