Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 3/20 | 0.53 |
| ▸ | GABRD | O14764 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.53 |
| ▸ | GABRE | P78334 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046903 | 0.89 | GABRP (0.52) | CYP1A1CYP1A2CYP1B1TDP1CSNK2A2 | |
| SCHEMBL24046746 | 0.84 | CYP1A1 (0.48) | CYP1A1CYP1A2CYP1B1TDP1CSNK2A2 | |
| SCHEMBL21801095 | 0.81 | TDP1 (0.64) | CYP1A1CYP1A2CYP1B1TDP1CSNK2A2 | |
| SCHEMBL311865 | 0.78 | TERT (0.68) | CYP1A1CYP1A2CYP1B1TDP1CSNK2A2 | |
| SCHEMBL27676687 | 0.78 | CYP1A2 (0.65) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL24046901 | 0.76 | CSNK2A2 (0.45) | CYP1A1CYP1A2CYP1B1TDP1CSNK2A2 | |
| SCHEMBL6613777 | 0.75 | TERT (0.76) | CYP1A1CYP1A2CYP1B1TDP1GABRP | |
| SCHEMBL10988521 | 0.74 | CYP1A1 (0.63) | CYP1A1CYP1A2CYP1B1GABRPGABRD | |
| SCHEMBL10983495 | 0.74 | CYP1A1 (0.63) | CYP1A1CYP1A2CYP1B1GABRPGABRD | |
| SCHEMBL24046989 | 0.74 | TNKS (0.51) | CYP1A1CYP1A2CYP1B1TDP1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |