Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.51 |
| ▸ | GABRP | O00591 | 7/20 | 0.49 |
| ▸ | GABRD | O14764 | 7/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.49 |
| ▸ | GABRE | P78334 | 7/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046995 | 0.85 | TNKS (0.47) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24046903 | 0.85 | GABRP (0.52) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24046996 | 0.84 | CYP1B1 (0.49) | TNKSCYP1A1CYP1A2CYP1B1AR | |
| SCHEMBL24046901 | 0.77 | CSNK2A2 (0.45) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21784237 | 0.75 | PRKDC (0.47) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24046747 | 0.74 | CYP1A1 (0.57) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24046905 | 0.73 | CYP1A1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31632272 | 0.72 | TNKS (0.53) | TNKSGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24046753 | 0.71 | ALOX15 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24046894 | 0.69 | TNKS (0.56) | TNKSGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |