Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 10/20 | 0.71 |
| ▸ | PARP1 | P09874 | 5/20 | 0.71 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | DHODH | Q02127 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.71 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046904 | 0.84 | TNKS (0.61) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL345706 | 0.83 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL29664745 | 0.83 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL24046902 | 0.83 | TNKS (0.64) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL24046782 | 0.82 | CSNK2A2 (0.71) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL311918 | 0.80 | TNKS (0.76) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL311639 | 0.80 | TNKS (0.76) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL127446 | 0.77 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL29773081 | 0.77 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2KDM4E | |
| SCHEMBL31740082 | 0.76 | CSNK2A2 (1.00) | TNKSPARP1TNKS2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |