SCHEMBL29664745

SCHEMBL29664745

O=c1cc(-c2ccc(O)c(O)c2)oc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 10/20 1.00
PARP1 P09874 6/20 1.00
TNKS2 Q9H2K2 6/20 1.00
KDM4E B2RXH2 4/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
CYP3A4 P08684 4/20 1.00
ALOX5 P09917 4/20 1.00
POLH Q9Y253 3/20 1.00
MAPT P10636 3/20 1.00
MAPK1 P28482 3/20 1.00
HPGD P15428 3/20 1.00
FTO Q9C0B1 2/20 1.00
ALOX15 P16050 2/20 1.00
HSD17B10 Q99714 2/20 1.00
IP6K2 Q9UHH9 2/20 1.00
ALDH1A1 P00352 1/20 1.00
ST6GAL1 P15907 1/20 1.00
DHODH Q02127 1/20 1.00
RAB9A P51151 3/20 0.72
NPC1 O15118 3/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345706 1.00 TNKS (1.00) TNKSPARP1TNKS2KDM4ESMN1; SMN2
SCHEMBL311639 0.87 TNKS (0.76) TNKSPARP1TNKS2KDM4ESMN1; SMN2
SCHEMBL311918 0.87 TNKS (0.76) TNKSPARP1TNKS2KDM4ESMN1; SMN2
SCHEMBL1883775 0.86 FTO (1.00) TNKSPARP1TNKS2KDM4ESMN1; SMN2
SCHEMBL30000045 0.86 FTO (1.00) TNKSPARP1TNKS2KDM4ESMN1; SMN2
Flavone SCHEMBL27987776 0.86 TNKS (0.84) TNKSPARP1TNKS2KDM4ESMN1; SMN2
SCHEMBL31387550 0.85 MAPT (0.74) TNKSPARP1TNKS2KDM4ESMN1; SMN2
Luteolin SCHEMBL30913900 0.85 POLH (0.75) TNKSPARP1TNKS2KDM4ESMN1; SMN2
Luteolin SCHEMBL1229732 0.85 POLH (0.75) TNKSPARP1TNKS2KDM4ESMN1; SMN2
Luteolin SCHEMBL15271260 0.85 POLH (0.75) TNKSPARP1TNKS2KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085410-A Boron-based natural flavone brucite composite powder and preparation method and application thereof 江西广源新材料有限公司 2024-05-28 CN claimed
CN-116829544-A Synthesis method of flavonoid dimers and oligomers and application thereof 新加坡国立大学 2023-09-29 CN claimed
EP-4003522-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-06-01 EP claimed
US-20250368629-A1 FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS MAYO FOUND MEDICAL EDUCATION & RES (US) 2025-12-04 US disclosed
CN-119365193-A Flavonoid compounds and methods and materials for treating fibrotic disorders using flavonoid compounds 梅约医学教育与研究基金会 2025-01-24 CN disclosed
WO-2025019587-A1 SENOTHERAPEUTIC COMPOUNDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2025-01-23 WO disclosed
CN-118530493-A Protective film, protective film agent, and method for processing workpiece 株式会社迪思科 2024-08-23 CN disclosed
CN-118085410-A Boron-based natural flavone brucite composite powder and preparation method and application thereof 江西广源新材料有限公司 2024-05-28 CN disclosed
CN-118001403-A Method for preparing phosphoric acid nano-drug based on competitive coordination and multifunctional nano-drug 吉林大学 2024-05-10 CN disclosed
US-20240122894-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-04-18 US disclosed
EP-4259614-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF National University of Singapore (SG) 2023-10-18 EP disclosed
CN-116829544-A Synthesis method of flavonoid dimers and oligomers and application thereof 新加坡国立大学 2023-09-29 CN disclosed
CN-115948362-A Oxygen methyltransferase participating in biosynthesis of polymethoxyflavone in citrus peel, coding gene, amplification primer pair and application 浙江大学 2023-04-11 CN disclosed
CN-115785742-A Protective film agent and method for processing processed object 株式会社迪思科 2023-03-14 CN disclosed
WO-2022124994-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-06-16 WO disclosed
EP-4003522-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122894-A1 METHODS TO SYNTHESIZE FLAVONOID DIMERS AND OLIGOMERS AND THE USE THEREOF ERG28, MGAM, CTRB2 TNKS 3615/4885PARP1 3677/4885TNKS2 2755/4885
US-20250368629-A1 FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS FABP1, FN1, MMP1 TNKS 3668/4885PARP1 2251/4885TNKS2 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.