Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046905 | 0.88 | CYP1A1 (0.44) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL24046901 | 0.86 | CSNK2A2 (0.45) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL24046746 | 0.79 | CYP1A1 (0.48) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL24046903 | 0.73 | GABRP (0.52) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL311288 | 0.70 | LOXL2 (0.47) | CYP1B1CYP1A1CYP1A2CCNT1CDK7 | |
| SCHEMBL24046989 | 0.66 | TNKS (0.51) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL24046990 | 0.66 | CSNK2A2 (0.50) | CYP1B1CYP1A1CYP1A2GABRPGABRD | |
| SCHEMBL312714 | 0.65 | TNKS (0.62) | CYP1B1CYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL24046996 | 0.64 | CYP1B1 (0.49) | CYP1B1CYP1A1CYP1A2CSNK2A2CSNK2B | |
| SCHEMBL311280 | 0.64 | HPGD (0.61) | CYP1B1CYP1A2ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |