SCHEMBL312254

SCHEMBL312254

COc1ccc2c(=O)cc(-c3ccc(O)cc3)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 1.00
KDM4E B2RXH2 7/20 1.00
ALDH1A1 P00352 6/20 1.00
HPGD P15428 6/20 1.00
TP53 P04637 5/20 1.00
MAPT P10636 5/20 1.00
HSD17B10 Q99714 5/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
CYP2C9 P11712 3/20 1.00
CYP2C19 P33261 3/20 1.00
CYP2D6 P10635 2/20 1.00
TNKS O95271 4/20 0.87
TNKS2 Q9H2K2 1/20 0.87
MAOB P27338 7/20 0.83
MAPK1 P28482 3/20 0.82
TSHR P16473 1/20 0.82
CYP19A1 P11511 3/20 0.74
NPC1 O15118 4/20 0.73
RAB9A P51151 4/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30266579 1.00 CYP3A4 (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL30120666 0.93 CYP3A4 (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL534596 0.93 CYP3A4 (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
4,7-Dimethoxyflavone SCHEMBL3470601 0.91 MAOB (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL4650062 0.90 MAPT (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL31675778 0.90 MAPT (1.00) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL9663461 0.88 CSNK2A2 (0.87) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL31238403 0.87 MAPT (0.92) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL4160578 0.86 CSNK2A2 (0.81) CYP3A4KDM4EALDH1A1HPGDTP53
SCHEMBL9142214 0.86 MAOB (1.00) CYP3A4KDM4EALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
US-5141745-A Gene expression THE LUBRIZOL CORPORATION (US) 1992-08-25 US claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
US-20250263774-A1 DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD UNIV NORTH TEXAS (US) 2025-08-21 US disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
WO-2021236578-A1 CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2021-11-25 WO disclosed
US-20210346385-A1 TASTE-MASKED DOSAGE FORMS DEEP OCEAN CAPITAL MANAGEMENT LP 2021-11-11 US disclosed
WO-2020061584-A1 TASTE-MASKED DOSAGE FORMS MSB HOLDINGS, INC. (US) 2020-03-26 WO disclosed
EP-2730431-B1 Rubber composition and tire with rubber containing flavone GOODYEAR TIRE & RUBBER (US) 2017-06-28 EP disclosed
US-5229113-A Gene expression, soybeans LUBRIZOL GENETICS, INC. (US) 1993-07-20 US disclosed
US-5141745-A Gene expression THE LUBRIZOL CORPORATION (US) 1992-08-25 US disclosed
US-5141745-A Gene expression THE LUBRIZOL CORPORATION (US) 1992-08-25 US disclosed
US-5023180-A Bradyrhizobium japonicum nodulation regulatory protein and gene LUBRIZOL GENETICS, INC. (US) 1991-06-11 US disclosed
EP-0245931-A3 NODULATION INDUCING FACTORS LUBRIZOL GENETICS INC. (US) 1989-04-12 EP disclosed
EP-0269725-A4 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE. LUBRIZOL GENETICS INC (US) 1989-01-12 EP disclosed
EP-0269725-A1 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE LUBRIZOL GENETICS INC. (US) 1988-06-08 EP disclosed
WO-1987007910-A1 BRADYRHIZOBIUM JAPONICUM NODULATION REGULATORY PROTEIN AND GENE LUBRIZOL GENETICS, INC. (US) 1987-12-30 WO disclosed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL CYP3A4 3591/4885KDM4E 984/4885ALDH1A1 4390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.